Hippocrates Health Search Results from the Invisible Web

zofran: Health Search Results from the Invisible Web

Health Search Results powered by CloserLook Search
:: Overview :: Precautions :: Side Effects :: Further Reading Search results last updated: 5/9/2009

Generic & Brand Name : Source: (RXList)

Brand Name : Zofran
Generic Name : Ondansetron Hydrochloride

Overview (Source: MedicineNet)
home > ondansetron 32 mg-injection index > ondansetron 32 mg-injection, zofran drug monograph ...
[ read more.. ]

Get A Second Opinion From...
DrugInfoOnlinezofran

Precautions (Source: RXList)
Hypersensitivity reactions have been reported in patients who have exhibited hypersensitivity to other selective 5-HT 3 receptor antagonists. ...
[ read more.. ]

Side Effects (Source: RXList)
The following have been reported as adverse events in clinical trials of patients treated with ondansetron, the active ingredient of ZOFRAN . A causal relationship to therapy with ZOFRAN has been unclear in many cases. Chemotherapy-Induced Nausea and Vomiting: The adverse events in Table 5 have been reported in ≥ 5% of adult patients receiving a single 24-mg ZOFRAN Tablet in 2 trials. These patients were receiving concurrent highly emetogenic cisplatin-based chemotherapy regimens ( cisplatin dose ≥ 50 mg/m²). Table 5. Principal Adverse Events in US Trials: Single Day Therapy With 24-mg ZOFRAN Tablets (Highly Emetogenic Chemotherapy) Event Ondansetron 24 mg q.d. n = 300 Ondansetron 8 mg b.i.d. n = 124 Ondansetron 32 mg q.d. n = 117 Headache 33 (11%) 16 (13%) 17 (15%) Diarrhea 13 (4%) 9 (7%) 3 (3%) The adverse events in Table 6 have been reported in 5% of adults receiving either 8 mg of ZOFRAN Tablets 2 or 3 times a day for 3 days or placebo in 4 trials. These patients were receiving concurrent moderately emetogenic chemotherapy, primarily cyclophosphamide-based regimens. Table 6. Principal Adverse Events in US Trials: 3 Days of Therapy With 8-mg ZOFRAN Tablets (Moderately Emetogenic Chemotherapy) Event Ondansetron 8 mg b.i.d . n = 242 Ondansetron 8 mg t.i.d. n = 415 Placebo n = 262 Headache 58 (24%) 113 (27%) 34 (13%) Malaise/fatigue 32 (13%) 37 (9%) 6 (2%) Constipation 22 (9%) 26 (6%) 1 ( Diarrhea 15 (6%) 16 (4%) 10 (4%) Dizziness 13 (5%) 18 (4%) 12 (5%) Central Nervous Syste ...
[ read more.. ]

Get A Second Opinion From...
DrugInfoOnline zofran

Further Reading on zofran
  • Non-Small-Cell Lung Cancer ( WebMD )
    Non – small - cell lung cancer ( NSCLC ) is a catchall term for the 75 % of all lung cancers that are not small - cell type ; they are ...receptor antagonists, which include ondansetron ( Zofran ), granisetron...
  • Gastroenteritis ( WebMD )
    Gastroenteritis is a condition that causes irritation and inflammation of the stomach and intestines ...Phenergan, Anergan), prochlorperazine (Compazine), or ondansetron ( Zofran ). Sometimes these...

DISCLAIMER: The content provided by this site and/or this page is for information purposes only. Closerlook Search Services Inc. does not warrant or guarantee accuracy or timeliness of any information returned on this page even if such information appears in any search results accessed through Closerlook Search Services Inc. website properties.