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:: Overview :: Precautions :: Side Effects Search results last updated: 5/9/2009

Generic & Brand Name : Source: (RXList)

Brand Name : Ziagen
Generic Name : Abacavir Sulfate

Overview (Source: MedicineNet)
Abacavir is an oral medication that is used for the treatment of infections with the human immunodeficiency virus (HIV). It is in a class of drugs called reverse transcriptase inhibitors which also includes zalcitabine (Hivid), zidovudine (Retrovir), didanosine (Videx), lamivudine (Epivir) and stavudine (Zerit). During infection with HIV, the HIV virus multiplies within the body's cells. The newly-formed viruses then are released from the cells and spread throughout the body where they infect other cells. In this manner, the infection continually spreads to new, uninfected cells that the body is continually producing, and HIV infection is perpetuated. When producing new viruses, the HIV virus must manufacture new DNA for each virus. Reverse transcriptase is the enzyme that the virus uses to form this new DNA. Specifically, abacavir is converted within the body to its active form (carbovir triphosphate). This active form is similar to a compound (deoxyguanosine triphosphate), a chemical that is required by the HIV virus to make new DNA. The reverse transcriptase uses carbovir triphosphate instead of deoxyguanosine triphosphate for making DNA, and it is the carbovir triphosphate that interferes with the reverse transcriptase. Abacavir does not kill existing HIV virus and it is not a cure for HIV. The FDA approved abacavir in December, 1998. ...
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DrugDigestziagen

Precautions (Source: RXList)
Included as part of the PRECAUTIONS section. ...
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DrugDigest ziagen

Side Effects (Source: DrugDigest)
Side effects that you should report to your doctor or health care professional as soon as possible: allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue breathing difficulties, cough fever, chills, sore throat, infection nausea, vomiting, diarrhea, stomach pain redness, blistering, peeling or loosening of the skin, including inside the mouth unexplained weight loss unusually weak or tired Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome): headache loss of appetite difficulty sleeping weight gain around waist, back, or thinning of face, arms, legs This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. ...
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RXList Side Effects & Drug Interactions
DrugInfoOnline ziagen

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