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:: Overview :: Precautions :: Side Effects :: News :: Further Reading Search results last updated: 5/9/2009

Generic & Brand Name : Source: (RXList)

Brand Name : Taxotere
Generic Name : Docetaxel for Injection

Overview (Source: MedicineNet)
Docetaxel is a cancer drug that is used for treating breast cancer . Docetaxel works by attacking cancer cells. Different medications attack cancer cells in different ways. Every cell in your body contains a supporting structure (almost like a skeleton) called the microtubular network. If this "skeleton" is changed or damaged, the cell can't grow or reproduce. Taxotere makes the "skeleton" in cancer cells unnaturally stiff, so that these cells can no longer grow. ...
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Precautions (Source: RXList)
Included as part of the PRECAUTIONS section. ...
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Side Effects (Source: RXList)
Adverse reactions are described for TAXOTERE according to indication. Clinical Trial Experience Breast Cancer Monotherapy with TAXOTERE for locally advanced or metastatic breast cancer after failure of prior chemotherapy TAXOTERE 100 mg/m 2 : Adverse drug reactions occurring in at least 5% of patients are compared for three populations who received TAXOTERE administered at 100 mg/m 2 as a 1-hour infusion every 3 weeks: 2045 patients with various tumor types and normal baseline liver function tests; the subset of 965 patients with locally advanced or metastatic breast cancer, both previously treated and untreated with chemotherapy, who had normal baseline liver function tests; and an additional 61 patients with various tumor types who had abnormal liver function tests at baseline. These reactions were described using COSTART terms and were considered possibly or probably related to TAXOTERE. At least 95% of these patients did not receive hematopoietic support. The safety profile is generally similar in patients receiving TAXOTERE for the treatment of breast cancer and in patients with other tumor types (See Table 4 ). Table 4 - Summary of Adverse Reactions in Patients Receiving TAXOTERE at 100 mg/m 2 Adverse Reaction All Tumor Types Normal LFTs* n=2045 % All Tumor Types Elevated LFTs** n=61 % Breast Cancer Normal LFTs* n=965 % Hematologic       Neutropenia          3 95.5 96.4 98.5    3 75.4 87.5 85.9 Leukopenia          3 95.6 98.3 98.6    3 31.6 46.6 43.7 Thrombocytopenia   ...
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News on taxotere
Prostate cancer vaccine improves survival (ReutersHealth)

Further Reading on taxotere
  • Non-Small Cell Lung Cancer Treatment (PDQ®) - Treatment Option Overview ( WebMD )
    In non - small cell lung cancer ( NSCLC ), results of standard treatment are poor except for the most localized cancers . All newly ...carboplatin, paclitaxel (Taxol), docetaxel ( Taxotere ), topotecan,
  • Non-Small-Cell Lung Cancer ( WebMD )
    Non – small - cell lung cancer ( NSCLC ) is a catchall term for the 75 % of all lung cancers that are not small - cell type ; they are ...of DNA in cells so they cannot reproduce. Docetaxel ( Taxotere ): This...

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