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kernicterus - Definition: (Source: MedicineNet)

Kernicterus: A type of brain damage associated with athetoid cerebral palsy (uncontrollable movement of the face, body, arms, and legs) and deafness. Kernicterus is due to marked jaundice in the newborn period. The high blood level of the pigment bilirubin results in its deposition in the brain, which damages the brain. ...
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kernicterus - Images (Source: MedLinePlus)
Kernicterus
Kernicterus

About kernicterus (Source: WebMD)
Kernicterus is a very rare type of brain damage that occurs in a newborn with severe jaundice . It happens when a substance in the blood, called bilirubin , builds up to very high levels and spreads into the brain tissues. This causes permanent brain damage. ...
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eMedicineHealth Kernicterus

Frequently Asked Questions for kernicterus (Source: MedicineNet)
What is kernicterus?
Who can develop kernicterus?
Does jaundice always cause a problem?
Are some babies more likely to be jaundiced?
What are some warning signs of kernicterus?
Can jaundice be treated and prevent kernicterus from developing?
What should I do if I think my baby has jaundice?
Is there a support group for parents of children with kernicterus?

Causes of kernicterus (Source: MedLinePlus)
Kernicterus is caused by very high levels of bilirubin. Bilirubin is a yellow pigment that is created in the body during the normal recycling of old red blood cells. High levels of bilirubin in the body can cause the skin to look yellow (which is called jaundice). In some cases when there are extremely high levels of bilirubin in the body or the baby is extremely ill, the substance will move out of the blood and collect in the brain tissue. This can lead to serious neurological complications, including brain damage. Kernicterus usually develops in the first week of life, but may be seen up until the third week. Newborns with Rh hemolytic disease that leads to hydrops fetalis are at high risk for severe jaundice that leads to this condition. However, kernicterus has been seen in apparently healthy babies. ...
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WebMD What causes kernicterus

Symptoms of kernicterus (Source: MedLinePlus)
The symptoms depend on the stage of kernicterus. Early stage: Extreme jaundice; Absent startle reflex; Poor breast-feeding or sucking; Extreme sleepiness (lethargy). Mid stage: High-pitched cry; Arched back with neck hyperextended backwards; Bulging fontanel (soft spot); Seizures. Late stage (full neurological syndrome): High-frequency hearing loss; Mental retardation; Muscle rigidity; Speech difficulties; Seizures; Movement disorder. ...
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WebMD What are the symptoms of kernicterus

Further Reading on kernicterus
  • Jaundice in Newborns (Hyperbilirubinemia) - Treatment Overview ( WebMD )
    Most of the time no medical treatment is needed for jaundice in a newborn ( hyperbilirubinemia ). However , watch for increasing ...of bilirubin in the blood may lead to brain damage ( kernicterus ), which...
  • Jaundice in Newborns (Hyperbilirubinemia) - Topic Overview ( WebMD )
    Jaundice is a condition that causes a pronounced yellow tint to the skin and the white part of the ...rare cases, too much bilirubin in the blood can cause brain damage ( kernicterus ). This can lead...
  • Bilirubin ( WebMD )
    Bilirubin is a brownish yellow substance found in bile . It is produced when the liver breaks down ...bilirubin (hyperbilirubinemia) in a newborn baby can cause brain damage ( kernicterus ), hearing loss,

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