Kawasaki disease often begins with a high and persistent fever greater than 102°F, often as high as 104°F. A persistent fever lasting at least 5 days is considered a classic sign. The fever may last for up to 2 weeks and does not usually go away with normal doses of acetaminophen (Tylenol) or ibuprofen. Other symptoms often include: Extremely bloodshot or red eyes (without pus or drainage); Bright red, chapped, or cracked lips; Red mucous membranes in the mouth; Strawberry tongue, white coating on the tongue, or prominent red bumps on the back of the tongue; Red palms of the hands and the soles of the feet; Swollen hands and feet; Skin rashes on the middle of the body, NOT blister-like; Peeling skin in the genital area, hands, and feet (especially around the nails, palms, and soles); Swollen lymph nodes (frequently only one lymph node is swollen), particularly in the neck area; Joint pain and swelling, frequently one both sides of the body. Additional symptoms may include: Irritability; Diarrhea, vomiting, and abdominal pain; Cough and runny nose.
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