Transfusion reactions from incompatible blood Each person has a specific blood type, characterized by the ABO blood groups and the presence or absence of the Rh factor (Rh positive or Rh negative). Because reactions can occur if a person receives a transfusion of improper blood type, a system of checks and balances (known as typing and crossmatching ) and other safety procedures have been developed to prevent transfusion reactions. Such reactions vary from mild (fever or chills) to severe, such as ABO blood type incompatibility, which can be fatal.
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